A doctor who has helped thousands of cancer patients with hot spot mutations has developed a new treatment that can stop the progression of the disease and reverse the progression to aggressive cancer.
Johns Hot Spot cure is a cure for the cancer of the skin that is caused by mutations in the gene that encodes the protein that produces heat, according to the Australian Medical Association.
The Australian Medical Assn.
(AMA) said the treatment works by targeting the heat receptors of the melanoma cell, which is the primary target of the treatment.
Dr Jonathan Jones said the therapy was being developed for a patient with a mutated gene that had been found to cause the skin to become more sensitive to UV light.
“This is a very rare form of melanoma, and it is very rare that it is found in the skin of people who have had hot spots,” Dr Jones said.
“If the mutation occurs in people who do not have hot spots, we know that it can be prevented by an immunotherapy, so this could be a really useful intervention.”
The AMA said it was encouraging patients who had been told by their doctors to stop treatment and return to work to continue to get the treatment and follow it.
A study of more than 3,000 people who had received the treatment found about 60 per cent were doing well, with about half of them continuing to take the treatment for about 12 months after stopping treatment.
About one in three people with the mutated gene who started treatment stopped treatment, with the remaining patients being able to go back to work.
The AMA says about 30 per cent of people with melanoma diagnosed in the US who received the therapy have continued treatment for three years.
The American Cancer Society has been urging the US Government to allow doctors to use the treatment in other countries.
Australia’s chief medical officer, Dr Richard Albrecht, said a global consensus had emerged that hot spot treatments could be effective in the treatment of melanomas and that other cancers as well as the rare forms of cancer were likely to benefit from the new treatment.
“There are a number of different ways we can improve the quality of life for people with malignant melanoma,” Dr Albrecht said.
Melanoma is a form of skin cancer caused by the melanin in the hair follicles of the hair shaft.
It is the second most common skin cancer worldwide, with more than one million Australians diagnosed with the disease in 2015.
An estimated 70,000 Australians die from the disease each year.
People diagnosed with melanomas typically have less than a 1 per cent chance of developing the disease, but can have a 30 per year chance of survival.
In Australia, more than 70 per cent patients with malignancies will be cured.
More than 10,000 new melanomas are diagnosed in Australia each year and about one in five are caught early.
For the first time, the AMA has announced that it would not fund the controversial treatment in Australia, but has been encouraging Australians to try it out.
Earlier this month, the Australian Cancer Society said that its members would start to try the treatment at their hospitals, in addition to the private sector.
Australian National University Professor of Dermatology Dr Joanna McQuade said it would be a good test of the efficacy of the new drug.
She said that it might be a challenge for people to continue taking it for a longer period of time, but that patients should be able to get better on their own.
“I think the most exciting part about this is that it will be able in some ways to provide a model that will work in other cancers too,” Dr McQuades said.
Topics:cancer,therapy-and-medicine,research,health,melanoma,sunday-heritage-day,melbourne-3000,vic,united-states,australiaFirst posted April 30, 2019 08:42:54Contact Greg MurphyMore stories from Victoria